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SPM Active®

Targets the root causes of body soreness*

Fish Oils
Muscle, Bone & Joint
Wellness

New Year Savings: Get 20% off + free shipping. Use START2026 at checkout. Terms apply.

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SPM Active® renews the body's natural ability to soothe and minimize joint and muscle discomfort. Clinical research showed a decrease in joint soreness and discomfort intensity in two weeks.* ††

  • Formulated with next-generation omega fish oil for long-lasting relief.*
  • Now available in double the strength for convenient single daily dosage – learn more about SPM Active One Daily.
  • Backed by our 60-Day Money Back guarantee
†Based on loading dose with 2g SPM Active daily for 6 weeks
††36% of clinical study participants reported decreased soreness and discomfort after 2 weeks of supplementation with 1.5 g SPM Active daily. Callan N, et al. J Transl Med. 2020;18(1):401.

IngredientsAmount Per Serving% Daily Value
Serving Size2 Softgels
Servings Per Container60
Calories10
Total Fat1 g1%*
Cholesterol<5 mg<2%
Active Fractionated Marine Lipid Concentrate† SPM content standardized to 18-hydroxy-eicosapentaenoic acid (18-HEPE) 17-hydroxy-docosahexaenoic acid (17-HDHA) and 14-hydroxy-docosahexaenoic acid (14-HDHA).1 g**

Other Ingredients: Fractionated marine lipid concentrate [fish oil (anchovy, sardine, andmackerel) and mixed tocopherols (antioxidant)], softgel shell (gelatin, glycerin,and water), and silica. Contains: Fish (anchovy, sardine, and mackerel).



SKU: SPMA60

Directions: Take two softgels once daily or as directed by your healthcare practitioner.

Dry Place

Frequently bought together

  • SPM Active® One Daily

    Supports your body’s natural ability to recover from soreness and physical strain.*

    4.5
    SPM Active® One Daily
  • OsteoVantiv®

    Provides joint relief & supports joint flexibility.*

    5.0
    OsteoVantiv®
"A few years ago my knees were sore and I had hard time walking. SPM has been a life saver. Knees get sore periodically, but  more manageable. "
Dianne
The Science That Creates Balance®
Metagenics Special Ingredient Image
Metagenics delivers precision-crafted formulas to support your health—because true wellness starts with integrity, balance, & expertise.
Fish Oils
Muscle, Bone & Joint
Wellness

New Year Savings: Get 20% off + free shipping. Use START2026 at checkout. Terms apply.

Select Container Size

Select Flavor

SPM Active® renews the body's natural ability to soothe and minimize joint and muscle discomfort. Clinical research showed a decrease in joint soreness and discomfort intensity in two weeks.* ††

†Based on loading dose with 2g SPM Active daily for 6 weeks
††36% of clinical study participants reported decreased soreness and discomfort after 2 weeks of supplementation with 1.5 g SPM Active daily. Callan N, et al. J Transl Med. 2020;18(1):401.

IngredientsAmount Per Serving% Daily Value
Serving Size2 Softgels
Servings Per Container60
Calories10
Total Fat1 g1%*
Cholesterol<5 mg<2%
Active Fractionated Marine Lipid Concentrate† SPM content standardized to 18-hydroxy-eicosapentaenoic acid (18-HEPE) 17-hydroxy-docosahexaenoic acid (17-HDHA) and 14-hydroxy-docosahexaenoic acid (14-HDHA).1 g**

Other Ingredients: Fractionated marine lipid concentrate [fish oil (anchovy, sardine, andmackerel) and mixed tocopherols (antioxidant)], softgel shell (gelatin, glycerin,and water), and silica. Contains: Fish (anchovy, sardine, and mackerel).



SKU: SPMA60

Directions: Take two softgels once daily or as directed by your healthcare practitioner.

Dry Place

Frequently bought together

  • SPM Active® One Daily

    Supports your body’s natural ability to recover from soreness and physical strain.*

    4.5
    SPM Active® One Daily
  • OsteoVantiv®

    Provides joint relief & supports joint flexibility.*

    5.0
    OsteoVantiv®
  • Rapid Relief

    Fast-acting, drug-free pain relief for muscle and joint soreness*

    4.2

    New

    Rapid Relief

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