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SPM Active® One Daily

Supports your body’s natural ability to recover from soreness and physical strain.*

Fish Oils
Muscle, Bone & Joint
Wellness

New to Metagenics? Get 30% off + free shipping on your first order. Use 30OFF at checkout. Terms apply.

Select Container Size

SPM Active® One Daily helps your body feel better—fast. In just 14 days, this once-a-day softgel helps ease everyday soreness and joint discomfort so you can move more freely.*†

  • Relieves everyday soreness to help you feel more comfortable.*
  • Supports joint health so you can stay active with ease.*
  • Helps your body bounce back after physical activity or daily stress.*
  • Promotes relief by complementing the SPMs naturally produced in your body.*
  • Case studies show taking SPM Active® daily for 8 weeks led to improvements in mood, mental clarity, stress, and fatigue.*
  • Within 24 hours, immune cells respond smarter—strengthening protection while reducing damage to your body.*††
  • Specialized pro-resolving mediators (SPMs) are concentrated lipid compounds derived from omega-3 fatty acids in fish oil that support the body’s natural ability to resolve soreness and inflammation.*
  • SPMs are naturally found in the body, but our SPM levels decrease as we age, leading to increased rates of muscle and joint soreness.*
  • Metagenics pioneered supplementation of SPMs, offering the first-ever SPM product to help you reduce joint pain and soreness, and boost immune response.*

What customers can expect with consistent use:

  • Two weeks: 36% Felt less sore.
  • One Month: 77% of subjects had less joint discomfort
  • Three Months: 81% had less joint discomfort

What makes SPM Active® One Daily unique?

  • Clinically Studied, Next-Generation Fish Oil: Delivers specialized pro-resolving mediators (SPMs)—compounds derived from concentrated omega-3s that help ease minor joint discomfort and support faster recovery after physical stress or exercise.*
  • Renews the Body’s Natural Ability to Relieve Discomfort: Scientifically formulated to support the body’s natural inflammatory process—rather than simply mask symptoms—to help promote long-term joint and tissue health.*
  • Convenient Once-Daily Dose: Requires only one easy-to-swallow softgel per day to help maintain comfort with a simple daily routine.

Science-Backed & Third-Party Tested

  • Quality: Formulated with clinically tested ingredients.
  • Purity: Our fish oil is guaranteed to be pure, wild caught, and sustainably sourced.
  • Trusted by Healthcare Practitioners: Metagenics is the #1 Doctor-Recommended Professional Supplement Brand.
  • Science You Can Trust: Third-party tested and recommended by over 50,000 healthcare professionals.

How to Take SPM Active® One Daily:

  • Dosage: Take one softgel once daily or as directed by your healthcare practitioner.
  • Best For: Adults seeking effective relief for body soreness and joint discomfort. If you are pregnant, nursing, or taking medication, consult your healthcare practitioner before use. Keep out of the reach of children.
  • Safe for Daily Use: Safe and gentle for everyday use—one softgel per day.

Clean and Trusted Formula

Non-GMO | Gluten-Free | Sugar-Free | Lactose-Free


Disclaimers

36% of clinical study participants reported decreased soreness and discomfort after 2 weeks of supplementation with 1.5 g SPM Active daily. Callan N, et al. _J Transl Med_. 2020;18(1):401. ††Research conducted on an earlier emulsion version of SPM Active® with lower SPM content

Amount Per Serving% Daily Value
Serving Size1 Softgel
Servings Per Container14
Calories10
Total Fat1 g1%**
Cholesterol<5 mg<2%
Active Fractionated Marine Lipid Concentrate†1 g***
SPM content standardized to
18-hydroxy-eicosapentaenoic acid (18-HEPE)
17-hydroxy-docosahexaenoic acid (17-HDHA)
14-hydroxy-docosahexaenoic acid (14-HDHA)
*Percent Daily Values are based on a 2,000 calorie diet.
***Daily Value not established.

Ingredients: Fractionated marine lipid concentrate [fish oil (anchovy, sardine, and mackerel) and mixed tocopherols (antioxidant)], softgel shell (gelatin, glycerin, and water), and silica. Contains: Fish (anchovy, sardine, and mackerel).


SKU: SPMAD14

Take one softgel once daily or as directed by your healthcare practitioner.

Dry Place or Refrigerate

  • If pregnant, nursing, or taking medications, consult your healthcare practitioner before use. Keep out of the reach of children.

Frequently bought together

"I've used this product for two weeks and noticed an improvement in my joints. Less popping better movement."
Michael
The Science That Creates Balance®
Metagenics Special Ingredient Image
Metagenics delivers precision-crafted formulas to support your health—because true wellness starts with integrity, balance, & expertise.
Fish Oils
Muscle, Bone & Joint
Wellness

New to Metagenics? Get 30% off + free shipping on your first order. Use 30OFF at checkout. Terms apply.

Select Container Size

SPM Active® One Daily helps your body feel better—fast. In just 14 days, this once-a-day softgel helps ease everyday soreness and joint discomfort so you can move more freely.*†

  • Relieves everyday soreness to help you feel more comfortable.*
  • Supports joint health so you can stay active with ease.*
  • Helps your body bounce back after physical activity or daily stress.*
  • Promotes relief by complementing the SPMs naturally produced in your body.*
  • Case studies show taking SPM Active® daily for 8 weeks led to improvements in mood, mental clarity, stress, and fatigue.*
  • Within 24 hours, immune cells respond smarter—strengthening protection while reducing damage to your body.*††
  • Specialized pro-resolving mediators (SPMs) are concentrated lipid compounds derived from omega-3 fatty acids in fish oil that support the body’s natural ability to resolve soreness and inflammation.*
  • SPMs are naturally found in the body, but our SPM levels decrease as we age, leading to increased rates of muscle and joint soreness.*
  • Metagenics pioneered supplementation of SPMs, offering the first-ever SPM product to help you reduce joint pain and soreness, and boost immune response.*

What customers can expect with consistent use:

  • Two weeks: 36% Felt less sore.
  • One Month: 77% of subjects had less joint discomfort
  • Three Months: 81% had less joint discomfort

What makes SPM Active® One Daily unique?

  • Clinically Studied, Next-Generation Fish Oil: Delivers specialized pro-resolving mediators (SPMs)—compounds derived from concentrated omega-3s that help ease minor joint discomfort and support faster recovery after physical stress or exercise.*
  • Renews the Body’s Natural Ability to Relieve Discomfort: Scientifically formulated to support the body’s natural inflammatory process—rather than simply mask symptoms—to help promote long-term joint and tissue health.*
  • Convenient Once-Daily Dose: Requires only one easy-to-swallow softgel per day to help maintain comfort with a simple daily routine.

Science-Backed & Third-Party Tested

  • Quality: Formulated with clinically tested ingredients.
  • Purity: Our fish oil is guaranteed to be pure, wild caught, and sustainably sourced.
  • Trusted by Healthcare Practitioners: Metagenics is the #1 Doctor-Recommended Professional Supplement Brand.
  • Science You Can Trust: Third-party tested and recommended by over 50,000 healthcare professionals.

How to Take SPM Active® One Daily:

  • Dosage: Take one softgel once daily or as directed by your healthcare practitioner.
  • Best For: Adults seeking effective relief for body soreness and joint discomfort. If you are pregnant, nursing, or taking medication, consult your healthcare practitioner before use. Keep out of the reach of children.
  • Safe for Daily Use: Safe and gentle for everyday use—one softgel per day.

Clean and Trusted Formula

Non-GMO | Gluten-Free | Sugar-Free | Lactose-Free


Disclaimers

36% of clinical study participants reported decreased soreness and discomfort after 2 weeks of supplementation with 1.5 g SPM Active daily. Callan N, et al. _J Transl Med_. 2020;18(1):401. ††Research conducted on an earlier emulsion version of SPM Active® with lower SPM content

Amount Per Serving% Daily Value
Serving Size1 Softgel
Servings Per Container14
Calories10
Total Fat1 g1%**
Cholesterol<5 mg<2%
Active Fractionated Marine Lipid Concentrate†1 g***
SPM content standardized to
18-hydroxy-eicosapentaenoic acid (18-HEPE)
17-hydroxy-docosahexaenoic acid (17-HDHA)
14-hydroxy-docosahexaenoic acid (14-HDHA)
*Percent Daily Values are based on a 2,000 calorie diet.
***Daily Value not established.

Ingredients: Fractionated marine lipid concentrate [fish oil (anchovy, sardine, and mackerel) and mixed tocopherols (antioxidant)], softgel shell (gelatin, glycerin, and water), and silica. Contains: Fish (anchovy, sardine, and mackerel).


SKU: SPMAD14

Take one softgel once daily or as directed by your healthcare practitioner.

Dry Place or Refrigerate

  • If pregnant, nursing, or taking medications, consult your healthcare practitioner before use. Keep out of the reach of children.

Frequently bought together

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