skip to content
Home
Cart
Welcome!

New Customer?Create Account

Serenagen®

Serenagen is a classic herbal stress management formula used in traditional Chinese medicine to nourish and quiet the heart.*

Stress, Mental Health
Sleep
Brain & Cognitive Health

New to Metagenics? Get 15% off your first order + free shipping! Auto-applied at checkout.

Select Container Size

Why you'll love Serenagen®

Serenagen® is a plant-based herbal supplement designed to help your body better handle everyday stress and support a calm, balanced mood.* This adaptogenic blend features traditional herbs like Rehmannia, Schisandra, Jujube, and Asian Ginseng to promote relaxation without drowsiness.* Taken daily, Serenagen® helps you stay centered, resilient, and composed—naturally.*


Triple tested. Practitioner trusted.

For over 40 years, Metagenics® has led innovation in health supplements, exceeding industry standards for transparency and accountability. We guarantee that what’s on the label is what’s in the bottle, and that commitment is why we’re trusted by more than 50,000 healthcare providers worldwide. This, and all our formulas are also:

  • Produced in GMP certified facilities to meet the highest quality standards.
  • Science-backed: We perform +200K quality tests annually, from ingredient sourcing to finished product, for accuracy and consistency.
  • Triple tested: All our products are verified for identity, purity, strength, and stability at three levels of production: ingredient, formula, and encapsulation.
  • Metagenics is the #1 Doctor-Recommended Professional Supplement Brand trusted by 50,000 healthcare practitioners.
  • Environmentally Responsible: As a registered B-Corp, sustainability matters; all our products are made ethically, responsibly, and with purpose.
  • Risk Free: Every purchase is backed by our 60-Day Money Back Guarantee.

Allergen Information

Non-GMO | Gluten-Free | Vegetarian

IngredientsAmount Per Serving% Daily Value
Serving Size2 Tablets
Servings Per Container30
Total Carbohydrate<1 g<1%**
Dietary Fiber<1 g2%**
A 4:1 Proprietary Herbal Extract Blend of: Rehmannia Root (Rehmannia glutinosa), Schisandra Fruit (Schisandra chinensis), Jujube Fruit (Ziziphus spinosa), Dong Quai Root (Angelica sinensis), Chinese Asparagus Root (Asparagus cochinchinensis), Ophiopogon Root (Ophiopogon japonicus), Scrophularia Root (Scrophularia ningpoensis), Asian Ginseng Root (Panax ginseng), Chinese Salvia Root (Salvia miltiorrhiza), Poria Fungus (Wolfiporia cocos), Polygala Root (Polygala tenuifolia), Platycodon Root (Platycodon grandiflorum)1 g***

Other Ingredients: Microcrystalline cellulose, croscarmellose sodium, cellulose, stearic acid (vegetable), silica, magnesium stearate (vegetable), and coating (hypromellose, medium-chain triglycerides, and hydroxypropylcellulose).



SKU: SE

Take two tablets daily or as directed by your healthcare practitioner.

Dry Place

  • Do not use if pregnant or nursing.

Frequently bought together

  • Adreset®

    Stress leaving you feeling drained? Support resilience & stamina with Adreset® adaptogen supplements

    4.8
    Adreset®
  • MethylCare®

    Supports vascular system by aiding the methylation process*

    4.8
    MethylCare®
  • NuSera®

    Relief for stressful moments.*

    NuSera®
A panel titled “Did You Know?” showing text about the high percentage of U.S. adults experiencing stress and noting that nutritional and herbal supplements can help with anxiety‑related conditions, with circular images of herbs.
A person sitting calmly and smiling beside text explaining that Serenagen combines time‑tested Traditional Chinese Medicine herbs to help the body adapt to stress, support emotional balance, promote calm non‑sedating focus, and support everyday resilience.
Two tablets shown with a Serenagen bottle in the background next to text instructing to take two tablets daily, with or without food, or as directed by a healthcare practitioner.
A hand holding a Serenagen bottle beside a customer review describing significant improvements in stress and thyroid‑related symptoms, shown with five stars and the name Maria V. as a verified customer.
Stress, Mental Health
Sleep
Brain & Cognitive Health

New to Metagenics? Get 15% off your first order + free shipping! Auto-applied at checkout.

Select Container Size

Why you'll love Serenagen®

Serenagen® is a plant-based herbal supplement designed to help your body better handle everyday stress and support a calm, balanced mood.* This adaptogenic blend features traditional herbs like Rehmannia, Schisandra, Jujube, and Asian Ginseng to promote relaxation without drowsiness.* Taken daily, Serenagen® helps you stay centered, resilient, and composed—naturally.*


Triple tested. Practitioner trusted.

For over 40 years, Metagenics® has led innovation in health supplements, exceeding industry standards for transparency and accountability. We guarantee that what’s on the label is what’s in the bottle, and that commitment is why we’re trusted by more than 50,000 healthcare providers worldwide. This, and all our formulas are also:

  • Produced in GMP certified facilities to meet the highest quality standards.
  • Science-backed: We perform +200K quality tests annually, from ingredient sourcing to finished product, for accuracy and consistency.
  • Triple tested: All our products are verified for identity, purity, strength, and stability at three levels of production: ingredient, formula, and encapsulation.
  • Metagenics is the #1 Doctor-Recommended Professional Supplement Brand trusted by 50,000 healthcare practitioners.
  • Environmentally Responsible: As a registered B-Corp, sustainability matters; all our products are made ethically, responsibly, and with purpose.
  • Risk Free: Every purchase is backed by our 60-Day Money Back Guarantee.

Allergen Information

Non-GMO | Gluten-Free | Vegetarian

IngredientsAmount Per Serving% Daily Value
Serving Size2 Tablets
Servings Per Container30
Total Carbohydrate<1 g<1%**
Dietary Fiber<1 g2%**
A 4:1 Proprietary Herbal Extract Blend of: Rehmannia Root (Rehmannia glutinosa), Schisandra Fruit (Schisandra chinensis), Jujube Fruit (Ziziphus spinosa), Dong Quai Root (Angelica sinensis), Chinese Asparagus Root (Asparagus cochinchinensis), Ophiopogon Root (Ophiopogon japonicus), Scrophularia Root (Scrophularia ningpoensis), Asian Ginseng Root (Panax ginseng), Chinese Salvia Root (Salvia miltiorrhiza), Poria Fungus (Wolfiporia cocos), Polygala Root (Polygala tenuifolia), Platycodon Root (Platycodon grandiflorum)1 g***

Other Ingredients: Microcrystalline cellulose, croscarmellose sodium, cellulose, stearic acid (vegetable), silica, magnesium stearate (vegetable), and coating (hypromellose, medium-chain triglycerides, and hydroxypropylcellulose).



SKU: SE

Take two tablets daily or as directed by your healthcare practitioner.

Dry Place

  • Do not use if pregnant or nursing.

Frequently bought together

  • Adreset®

    Stress leaving you feeling drained? Support resilience & stamina with Adreset® adaptogen supplements

    4.8
    Adreset®
  • MethylCare®

    Supports vascular system by aiding the methylation process*

    4.8
    MethylCare®
  • NuSera®

    Relief for stressful moments.*

    NuSera®

Customer Ratings & Reviews

Write A Review