Creatine UP®
More strength. More muscle. Powered by creatine, betaine and taurine to fuel performance.*†
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Why you'll love Creatine UP®
Creatine UP goes beyond just creatine. It's a 3-in-1 powerhouse combining clinically studied creatine monohydrate with two key osmolytes, betaine and taurine, to fuel your performance and recovery.
- Increases muscle strength & power output*
- Supports ATP recovery for repeated bursts of energy*
- Promotes lean muscle growth & endurance*
- Enhances high-intensity training performance and delays fatigue*
- Helps support muscle mass, hydration, and faster recovery*
Whether you’re focused on lifting more, training longer, or recovering faster, Creatine UP delivers foundational support to help you unlock measurable gains in strength, stamina, and performance.
Key ingredients explained
- Creatine Monohydrate – During exercise, your body rapidly depletes ATP (adenosine triphosphate), its primary energy source. Creatine helps replenish ATP stores, enabling you to push harder—whether you're lifting, sprinting, or grinding through a tough circuit. It also supports lean muscle growth and improved strength when used consistently with exercise.*
- Osmolytes Taurine + Betaine – These cellular hydration agents help muscles retain water, maintain cell volume, and resist fatigue. Taurine plays a vital role in skeletal muscle function, while betaine supports methylation and endurance. Together, they help optimize hydration, support recovery, and protect against performance decline during intense training.*
How to take Creatine UP
Mix 1 scoop (8 g) daily with 8 oz of water or your beverage of choice. For best results, take Creatine UP 30 minutes before or immediately following exercise. Pairs well with a recovery supplement such as Perfect Protein (available in whey and vegan formulas).
To maximize your results, take 4 servings daily for 1 week, followed by 1-2 servings daily. On rest days, take 1-2 servings daily with a meal or as directed by a trainer, coach, or healthcare professional.
Science-backed & third-party tested
Our ingredients are supported by hundreds of clinical studies and human trials, and every Metagenics product is manufactured in NSF-certified facilities. Every batch is third-party tested for purity, potency, and safety. As the #1 doctor-recommended professional supplement brand, Metagenics is trusted by over 50,000 healthcare providers.
- Doctor-trusted and practitioner-recommended
- Third-party tested for quality and potency
- +25M bottles sold worldwide in the last year
- Risk-Free: Love it or your money back with our 60-day satisfaction guarantee
Allergen Info
Non-GMO | Gluten-Free | Vegetarian | Sugar-Free | Dairy-Free | Soy-Free
| Ingredients | Amount Per Serving | % Daily Value |
|---|---|---|
| Serving Size | 1 Scoop (8 g) | |
| Servings Per Container | 60 | |
| Calories | 30 | |
| Creatine Monohydrate | 5 g | * |
| Betaine (as betaine anhydrous) | 1 g | * |
| Taurine | 0.75 g | * |
SKU: CREUP60
Directions: Mix 1 scoop (8 g) daily with 8 oz of water or beverage of choice. For best results, take this product 30 minutes before exercise, or immediately following exercise with a recovery beverage such as Perfect Protein. For best results, take 4 servings daily for 1 week, followed by 1-2 servings daily. On rest days, take 1-2 servings daily with a meal or as directed by a trainer, coach, or healthcare professional.
Dry Place
Creatine UP®
Do not use if pregnant or nursing. Use below age of 18 only under the supervision of a healthcare practitioner. If taking other dietary supplements or medications consult with your healthcare professional prior to use.
Not for use in patients with severe liver, kidney, cardiovascular disease, or bipolar disorder.
Frequently bought together
PhytoMulti® Multivitamin
Supports cellular health, overall wellness, and healthy aging*
4.8UltraFlora® Balance Probiotic
Starter probiotic for daily gut support*
4.7L-Carnitine
Support for fat metabolism*
Muscle Gains Bundle
Post-workout muscle powders to build strength and recover faster. Magnesium, protein, creatine, BCAAs, electrolytes, and more—clinically backed for max results.
Select Container Size
Why you'll love Creatine UP®
Creatine UP goes beyond just creatine. It's a 3-in-1 powerhouse combining clinically studied creatine monohydrate with two key osmolytes, betaine and taurine, to fuel your performance and recovery.
- Increases muscle strength & power output*
- Supports ATP recovery for repeated bursts of energy*
- Promotes lean muscle growth & endurance*
- Enhances high-intensity training performance and delays fatigue*
- Helps support muscle mass, hydration, and faster recovery*
Whether you’re focused on lifting more, training longer, or recovering faster, Creatine UP delivers foundational support to help you unlock measurable gains in strength, stamina, and performance.
Key ingredients explained
- Creatine Monohydrate – During exercise, your body rapidly depletes ATP (adenosine triphosphate), its primary energy source. Creatine helps replenish ATP stores, enabling you to push harder—whether you're lifting, sprinting, or grinding through a tough circuit. It also supports lean muscle growth and improved strength when used consistently with exercise.*
- Osmolytes Taurine + Betaine – These cellular hydration agents help muscles retain water, maintain cell volume, and resist fatigue. Taurine plays a vital role in skeletal muscle function, while betaine supports methylation and endurance. Together, they help optimize hydration, support recovery, and protect against performance decline during intense training.*
How to take Creatine UP
Mix 1 scoop (8 g) daily with 8 oz of water or your beverage of choice. For best results, take Creatine UP 30 minutes before or immediately following exercise. Pairs well with a recovery supplement such as Perfect Protein (available in whey and vegan formulas).
To maximize your results, take 4 servings daily for 1 week, followed by 1-2 servings daily. On rest days, take 1-2 servings daily with a meal or as directed by a trainer, coach, or healthcare professional.
Science-backed & third-party tested
Our ingredients are supported by hundreds of clinical studies and human trials, and every Metagenics product is manufactured in NSF-certified facilities. Every batch is third-party tested for purity, potency, and safety. As the #1 doctor-recommended professional supplement brand, Metagenics is trusted by over 50,000 healthcare providers.
- Doctor-trusted and practitioner-recommended
- Third-party tested for quality and potency
- +25M bottles sold worldwide in the last year
- Risk-Free: Love it or your money back with our 60-day satisfaction guarantee
Allergen Info
Non-GMO | Gluten-Free | Vegetarian | Sugar-Free | Dairy-Free | Soy-Free
| Ingredients | Amount Per Serving | % Daily Value |
|---|---|---|
| Serving Size | 1 Scoop (8 g) | |
| Servings Per Container | 60 | |
| Calories | 30 | |
| Creatine Monohydrate | 5 g | * |
| Betaine (as betaine anhydrous) | 1 g | * |
| Taurine | 0.75 g | * |
SKU: CREUP60
Directions: Mix 1 scoop (8 g) daily with 8 oz of water or beverage of choice. For best results, take this product 30 minutes before exercise, or immediately following exercise with a recovery beverage such as Perfect Protein. For best results, take 4 servings daily for 1 week, followed by 1-2 servings daily. On rest days, take 1-2 servings daily with a meal or as directed by a trainer, coach, or healthcare professional.
Dry Place
Creatine UP®
Do not use if pregnant or nursing. Use below age of 18 only under the supervision of a healthcare practitioner. If taking other dietary supplements or medications consult with your healthcare professional prior to use.
Not for use in patients with severe liver, kidney, cardiovascular disease, or bipolar disorder.
Frequently bought together
PhytoMulti® Multivitamin
Supports cellular health, overall wellness, and healthy aging*
4.8UltraFlora® Balance Probiotic
Starter probiotic for daily gut support*
4.7L-Carnitine
Support for fat metabolism*
Muscle Gains Bundle
Post-workout muscle powders to build strength and recover faster. Magnesium, protein, creatine, BCAAs, electrolytes, and more—clinically backed for max results.
