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UltraFlora® Spectrum Probiotic

Broad-spectrum probiotic for upper and lower GI support, digestive comfort, and immunity

Digestion & Probiotics
Stress, Mental Health
Immune Health

New to Metagenics? Get 15% off your first order + free shipping! Auto-applied at checkout.

Select Container Size

Most probiotics target one area of the gut

UltraFlora® Spectrum is designed to support the full length of your digestive tract, from upper to lower GI, with seven clinically studied strains working together in one daily capsule.*

A true broad-spectrum, multi-strain probiotic for people who want comprehensive daily gut support without juggling multiple supplements.

Whether you are maintaining digestive balance, recovering from disruption, or supporting immune health rooted in the gut, Spectrum delivers 30 billion CFU of practitioner-formulated coverage.*

Looking for a simpler everyday formula? Explore UltraFlora® Balance for targeted daily digestive support.*


Why you'll love UltraFlora® Spectrum

  • 7 clinically researched strains selected for complementary benefits across the full GI tract
  • Includes Saccharomyces boulardii, a unique probiotic yeast studied for its role in antibiotic recovery and traveler's digestive support
  • Features NCFM®, one of the most well-researched probiotic strains in the world, with 330+ publications and 60+ human trials behind it
  • 30 billion CFU per capsule at date of expiration, not just at manufacture
  • One capsule daily for broad digestive and immune health support

Prefer a higher strain count? Compare with UltraFlora® Complete, our 9-strain alternative for broader digestive coverage.*


The Science Inside

Your digestive system is a connected ecosystem. Different areas of the GI tract benefit from different probiotic strains. UltraFlora® Spectrum combines seven clinically researched strains selected to support multidimensional gut balance.

Each capsule provides 30 billion live organisms, including:

  • Saccharomyces boulardii: Studied for its role in supporting gastrointestinal balance, including during travel and antibiotic use.*
  • Bifidobacterium lactis Bl-04 & Bi-07: Recognized for supporting gastrointestinal health and promoting favorable gut flora. Studied in immune response research.*
  • Lactobacillus acidophilus NCFM®: One of the most researched probiotic strains, evaluated in 330+ publications and 60+ human trials for digestive and immune support.*
  • Lactobacillus plantarum Lp-115: Studied for its role in maintaining a healthy gut environment.*
  • Streptococcus thermophilus St-21: Included to complement overall digestive support.*

Together, these strains provide broad-spectrum support for both upper and lower GI tract health.*


Why Strain Diversity Matters

Different probiotic strains perform different functions. A multi strain probiotic allows for complementary activity across the digestive tract.

Research shows:

  • Bifidobacterium lactis strains support gastrointestinal health and promote favorable gut flora.
  • Bifidobacterium lactis Bl-04 and Lactobacillus acidophilus NCFM® have been studied for immune response support.
  • Saccharomyces boulardii has been evaluated in research for supporting gastrointestinal balance during antibiotic use and travel.
  • Lactobacillus acidophilus NCFM® has demonstrated lactase activity and has been studied in digestive comfort research.

UltraFlora® Spectrum provides multidimensional daily support for both the upper and lower GI tract for digestive and immune health.*

Interested in next-generation gut barrier support? Discover UltraFlora® Triplebiotic with Akkermansia.*


Third-Party Tested. Practitioner Trusted.

For over 40 years, Metagenics® has led innovation in health supplements, exceeding industry standards for transparency and accountability. We guarantee that what’s on the label is what’s in the bottle, and that commitment is why we’re trusted by more than 50,000 healthcare providers worldwide. This, and all our formulas are also:

  • Produced in GMP and NSF-certified facilities to meet the highest quality standards.
  • Science-backed: We perform +200K quality tests annually, from ingredient sourcing to finished product, for accuracy and consistency.
  • Third-party Tested: All our products are independently verified for purity, potency, & safety.
  • Metagenics® is the #1 Doctor-Recommended Professional Supplement Brand trusted by 50,000 healthcare practitioners.
  • Environmentally Responsible: As a registered B-Corp, sustainability matters; all our products are made ethically, responsibly, and with purpose.
  • Risk Free: Every purchase is backed by our 60-Day Money Back Guarantee.

Allergen Information

Non-GMO | Gluten-free | Sugar-free | Dairy-free | Soy-free | Allergen-free | Vegetarian capsule | No fillers | No preservatives

IngredientsAmount Per Serving% Daily Value
Serving Size1 Capsule†
Servings Per Container30
A Proprietary Blend of: Saccharomyces boulardii, Bifidobacterium lactis Bi-07†††, Lactobacillus plantarum Lp-115, Lactobacillus salivarius Ls-33, Lactobacillus acidophilus NCFM†††, Streptococcus thermophilus St-21,Bifidobacterium lactis Bl-04300 mg** (30 billion CFU)††
**Daily Value not established.
†Vegetarian capsule††At date of expiration. †††Bi-07® and NCFM® are registered or licensed trademarks of International Flavors & Fragrances Inc. and are used under license.

Other Ingredients: Capsule (hydroxypropylmethylcellulose, sorbitol, silicon dioxide, and sodium copper chlorophyllin), microcrystalline
cellulose, stearic acid (vegetable), and silicon dioxide.



SKU: UFSP

Take one capsule daily or as directed by your healthcare professional. Designed for adults seeking daily gastrointestinal and immune support. Suitable for ongoing use as part of a balanced wellness routine.* If pregnant, nursing, or taking medication, consult your healthcare professional before use.

No Storage Instruction

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Person’s midsection shown against a green background beside text stating that the gut does more than digest food
Circular graphic showing seventy percent beside text explaining that most of the immune system lives in the gut
Row of Metagenics UltraFlora bottles beside text listing roles of a balanced gut including digestion, immune support, skin and emotional health, and daily wellbeing
Green bacterial imagery beside text describing UltraFlora staying active in the gut for twenty‑four hours, surviving stomach acid, and releasing good bacteria within thirty minutes.
Digestion & Probiotics
Stress, Mental Health
Immune Health

New to Metagenics? Get 15% off your first order + free shipping! Auto-applied at checkout.

Select Container Size

Most probiotics target one area of the gut

UltraFlora® Spectrum is designed to support the full length of your digestive tract, from upper to lower GI, with seven clinically studied strains working together in one daily capsule.*

A true broad-spectrum, multi-strain probiotic for people who want comprehensive daily gut support without juggling multiple supplements.

Whether you are maintaining digestive balance, recovering from disruption, or supporting immune health rooted in the gut, Spectrum delivers 30 billion CFU of practitioner-formulated coverage.*

Looking for a simpler everyday formula? Explore UltraFlora® Balance for targeted daily digestive support.*


Why you'll love UltraFlora® Spectrum

  • 7 clinically researched strains selected for complementary benefits across the full GI tract
  • Includes Saccharomyces boulardii, a unique probiotic yeast studied for its role in antibiotic recovery and traveler's digestive support
  • Features NCFM®, one of the most well-researched probiotic strains in the world, with 330+ publications and 60+ human trials behind it
  • 30 billion CFU per capsule at date of expiration, not just at manufacture
  • One capsule daily for broad digestive and immune health support

Prefer a higher strain count? Compare with UltraFlora® Complete, our 9-strain alternative for broader digestive coverage.*


The Science Inside

Your digestive system is a connected ecosystem. Different areas of the GI tract benefit from different probiotic strains. UltraFlora® Spectrum combines seven clinically researched strains selected to support multidimensional gut balance.

Each capsule provides 30 billion live organisms, including:

  • Saccharomyces boulardii: Studied for its role in supporting gastrointestinal balance, including during travel and antibiotic use.*
  • Bifidobacterium lactis Bl-04 & Bi-07: Recognized for supporting gastrointestinal health and promoting favorable gut flora. Studied in immune response research.*
  • Lactobacillus acidophilus NCFM®: One of the most researched probiotic strains, evaluated in 330+ publications and 60+ human trials for digestive and immune support.*
  • Lactobacillus plantarum Lp-115: Studied for its role in maintaining a healthy gut environment.*
  • Streptococcus thermophilus St-21: Included to complement overall digestive support.*

Together, these strains provide broad-spectrum support for both upper and lower GI tract health.*


Why Strain Diversity Matters

Different probiotic strains perform different functions. A multi strain probiotic allows for complementary activity across the digestive tract.

Research shows:

  • Bifidobacterium lactis strains support gastrointestinal health and promote favorable gut flora.
  • Bifidobacterium lactis Bl-04 and Lactobacillus acidophilus NCFM® have been studied for immune response support.
  • Saccharomyces boulardii has been evaluated in research for supporting gastrointestinal balance during antibiotic use and travel.
  • Lactobacillus acidophilus NCFM® has demonstrated lactase activity and has been studied in digestive comfort research.

UltraFlora® Spectrum provides multidimensional daily support for both the upper and lower GI tract for digestive and immune health.*

Interested in next-generation gut barrier support? Discover UltraFlora® Triplebiotic with Akkermansia.*


Third-Party Tested. Practitioner Trusted.

For over 40 years, Metagenics® has led innovation in health supplements, exceeding industry standards for transparency and accountability. We guarantee that what’s on the label is what’s in the bottle, and that commitment is why we’re trusted by more than 50,000 healthcare providers worldwide. This, and all our formulas are also:

  • Produced in GMP and NSF-certified facilities to meet the highest quality standards.
  • Science-backed: We perform +200K quality tests annually, from ingredient sourcing to finished product, for accuracy and consistency.
  • Third-party Tested: All our products are independently verified for purity, potency, & safety.
  • Metagenics® is the #1 Doctor-Recommended Professional Supplement Brand trusted by 50,000 healthcare practitioners.
  • Environmentally Responsible: As a registered B-Corp, sustainability matters; all our products are made ethically, responsibly, and with purpose.
  • Risk Free: Every purchase is backed by our 60-Day Money Back Guarantee.

Allergen Information

Non-GMO | Gluten-free | Sugar-free | Dairy-free | Soy-free | Allergen-free | Vegetarian capsule | No fillers | No preservatives

IngredientsAmount Per Serving% Daily Value
Serving Size1 Capsule†
Servings Per Container30
A Proprietary Blend of: Saccharomyces boulardii, Bifidobacterium lactis Bi-07†††, Lactobacillus plantarum Lp-115, Lactobacillus salivarius Ls-33, Lactobacillus acidophilus NCFM†††, Streptococcus thermophilus St-21,Bifidobacterium lactis Bl-04300 mg** (30 billion CFU)††
**Daily Value not established.
†Vegetarian capsule††At date of expiration. †††Bi-07® and NCFM® are registered or licensed trademarks of International Flavors & Fragrances Inc. and are used under license.

Other Ingredients: Capsule (hydroxypropylmethylcellulose, sorbitol, silicon dioxide, and sodium copper chlorophyllin), microcrystalline
cellulose, stearic acid (vegetable), and silicon dioxide.



SKU: UFSP

Take one capsule daily or as directed by your healthcare professional. Designed for adults seeking daily gastrointestinal and immune support. Suitable for ongoing use as part of a balanced wellness routine.* If pregnant, nursing, or taking medication, consult your healthcare professional before use.

No Storage Instruction

Frequently bought together

Frequently Asked Questions

A multi-strain probiotic combines several different bacterial (and sometimes yeast) strains in one formula. Different strains colonize different areas of the gut and provide different benefits.

UltraFlora® Spectrum uses 7 clinically studied strains selected to work together across both the upper and lower GI tract, delivering broader coverage than single-strain formulas. Think of it as a team, not a solo act. Try UltraFlora® Spectrum risk-free with our 60-day money-back guarantee.

Saccharomyces boulardii is a probiotic yeast, not a bacterium. That distinction matters because it functions differently in the gut and is naturally resistant to antibiotics, allowing it to continue supporting digestive balance even during antibiotic use.*

It has been studied in meta-analyses for its role in helping reduce antibiotic-associated diarrhea and supporting digestive balance during travel-related disruption.*

Most multi-strain probiotics do not include this unique yeast. UltraFlora® Spectrum does, offering broader, more resilient digestive support as part of your daily routine.*

More CFU is not always better. What matters is whether the strains are clinically studied at the dose provided and whether they survive to reach the gut. UltraFlora® Spectrum delivers 30 billion CFU per capsule guaranteed at date of expiration, not just at the time of manufacture. Every strain is included at a clinically meaningful level, not inflated to create a bigger number on the label.

Yes, with timing in mind. Take UltraFlora® Spectrum at least 2 to 3 hours before or after your antibiotic dose.

The inclusion of Saccharomyces boulardii is particularly relevant here: as a probiotic yeast, it is naturally resistant to antibiotics and has been studied specifically for preventing antibiotic-associated diarrhea. Supporting your gut during and after a course of antibiotics is one of the most impactful times to use a broad-spectrum probiotic.

Best if kept refrigerated.

UltraFlora® Spectrum contains live probiotic cultures, and refrigeration helps maintain maximum potency through the expiration date. We guarantee the CFU count on the label through expiration when stored as directed.

If you travel, short periods at room temperature won't ruin the product, but consistent refrigeration delivers the best results.

UltraFlora® Balance is a focused, 2-strain daily probiotic for foundational gut support.

UltraFlora® Complete is a 9-strain formula for broad, multi-benefit coverage including digestion, immunity, energy, and skin.

UltraFlora® Spectrum sits in between: 7 strains with 30 billion CFU, specifically designed for upper and lower GI coverage with the added benefit of Saccharomyces boulardii for antibiotic recovery and travel support.

Choose Spectrum when you want targeted, full-tract coverage with a unique yeast strain most probiotics don't include. Explore the full UltraFlora® line to find the best match for your goal.

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