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OmegaGenics® Fish Oil EPA-DHA 720 mg

3-in-1 fish oil supplement for heart, eye, and joint health*

Omega-3s & Fish Oil
Heart Health
Brain & Cognitive Health

New to Metagenics? Get 15% off your first order + free shipping! Auto-applied at checkout.

Select Container Size

Why OmegaGenics® 3-in-1 Fish Oil 720 mg EPA-DHA may be right for you

Omega-3s are essential nutrients your body simply can't make on its own, yet your heart, eyes, and joints depend on them daily. OmegaGenics® 3-in-1 Fish Oil 720 mg EPA-DHA is a high-quality, multi-benefit fish oil delivering 430 mg EPA and 290 mg DHA per softgel from 100% wild-caught fish and purified to the highest standards.

Why you'll love this OmegaGenics® fish oil:

  • Delivers 3-in-1 support: For heart, eye, and joint health.*
  • High potency: 720 mg of EPA and DHA per softgel
  • Everyday omega-3 support: Three key benefits supporting heart, eye, and joint health per daily dose*
  • Sustainably sourced: From wild-caught, small, cold-water fish for purity and sustainability
  • Better taste: Natural lemon-lime flavor for a clean finish and no fishy burps
  • Satisfaction Guaranteed: Love it within 60-days or your money back

The Science Inside

EPA and DHA are essential omega-3 fatty acids. Your body needs them daily, but most people can't get enough from diet alone. This formula delivers both, supporting 3 key benefits in daily use.*

  • EPA (eicosapentaenoic acid) — The heart and joint health omega-3. Supports cardiovascular health and helps keep your body's inflammatory response in balance. (430 mg per softgel)*
  • DHA (docosahexaenoic acid) — The eye omega-3. DHA supports eye health, focus, and clear vision. (290 mg per softgel)*
  • Natural lemon-lime flavor — A clean finish with no fishy aftertaste.

These omega-3s are sustainably sourced, Friend of the Sea certified, and rigorously purified to ensure quality you can trust:

  • Friend of the Sea Certified ensuring responsible sourcing and environmental protection
  • Rigorously tested for 200+ contaminants, including heavy metals, environmental toxins, and microplastics
  • Derived from wild-caught sardines, anchovies, and mackerel—small fish chosen for purity and sustainability

Third-Party Tested. Practitioner Trusted.

For over 40 years, Metagenics® has led innovation in health supplements, exceeding industry standards for transparency and accountability. We guarantee that what’s on the label is what’s in the bottle, and that commitment is why we’re trusted by more than 50,000 healthcare providers worldwide. This, and all our formulas are also:

  • Produced in GMP and NSF-certified facilities to meet the highest quality standards.
  • Science-backed - We perform +200K tests annually, from ingredient sourcing to finished product, for accuracy and consistency.
  • Third-party Tested - All our products are independently verified for purity, potency, & safety.
  • Metagenics® is the #1 Doctor-Recommended Professional Supplement Brand trusted by 50,000 healthcare practitioners.
  • Environmentally Responsible - As a registered B-Corp, sustainability matters; all our products are made ethically, responsibly, and with purpose.
  • Risk Free - Every purchase is backed by our 60-Day Money Back Guarantee.

What’s Inside (and What’s Not)

Contains fish (sardine, anchovy, mackerel) | Contains gelatin | Contains glycerin | Non-GMO | Gluten-free | Lactose-free | No artificial colors or flavors | No preservatives

†† Richter CK, Bowen KJ. Total long-chain n-3 fatty acid intake and food sources in the United States compared to recommended intakes: NHANES 2003-2008. Lipids. 2017;52(11):917-927.

(1) Chevalier, L. & Plourde, M. et al., 2021. Pharmacokinetics of supplemental omega-3 fatty acids: Acute increases in plasma EPA and DHA within 24 hours after ingestion. Journal of Nutrition. doi:10.1093/jn/nxaaa1444

(2) U.S. Department of Health and Human Services, National Institutes of Health, Office of Dietary Supplements. (2024). Omega-3 fatty acids: Fact sheet for health professionals. https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/

(3) Borja-Magno, A. et al. (2023) ‘Differential effects of high-dose omega-3 fatty acids on metabolism and inflammation in patients with obesity: Eicosapentaenoic and docosahexaenoic acid supplementation’, Frontiers in Nutrition, 10, p. Article 1156995. doi: 10.3389/fnut.2023.1156995

(4) Gubari, M. I. M., 2024. Effect of omega-3 fatty acid supplementation on markers of inflammation and endothelial function in patients with chronic heart disease: A systematic review and meta-analysis. Cellular and Molecular Biology, 70(6), pp.171–177. doi:10.14715/cmb/2024.70.6.26.

(5)Xie, L. et al. (2025) ‘Effects of omega-3 fatty acids on chronic pain: A systematic review and meta-analysis’, Frontiers in Medicine, 12, Article 1654661. doi:10.3389/fmed.2025.1654661.

(6)Stavrinou, P. S. et al. (2020) ‘The effects of a 6-month high dose omega-3 and omega-6 polyunsaturated fatty acids and antioxidant vitamins supplementation on cognitive function and functional capacity in older adults with mild cognitive impairment’, Nutrients, 12(2), p. 325. doi:10.3390/nu12020325.

IngredientsAmount Per Serving% Daily Value
Serving Size2 Softgels
Servings Per Container30
Calories25
Calories from Fat25
Total Fat2.5 g3%**
Cholesterol5 mg2%
Marine Lipid Concentrate2.5 g***
EPA (Eicosapentaenoic acid)860 mg***
DHA (Docosahexaenoic acid)580 mg***
Other Omega-3 Fatty Acids160 mg***
**Percent Daily Values are based on a 2,000 calorie diet.***Daily Value not established.

Other Ingredients: Marine lipid concentrate [fish (sardine, anchovy, and mackerel) oil], softgel shell (gelatin, glycerin, water), contains 2 percent or less of natural lemon flavor, natural lime flavor, mixed tocopherols (antioxidant), rosemary extract, and ascorbyl palmitate (antioxidant). Contains: Fish (sardine, anchovy, and mackerel).



SKU: EPAL7

Take two softgels once daily with food or as directed by your healthcare practitioner.

Dry Place

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Educational graphic for Metagenics OmegaGenics® 3‑in‑1 Fish Oil 720 mg EPA‑DHA showing a single golden capsule on a light surface with text noting that over 90% of the U.S. population does not get enough EPA and DHA from diet alone.
Timeline graphic for Metagenics OmegaGenics® 3‑in‑1 Fish Oil 720 mg EPA‑DHA outlining how omega‑3 benefits may develop over time, including absorption within one day, rising levels over two weeks, improvements in eye comfort at one month, cardiometabolic and inflammatory marker changes by three months, and mood, clarity, processing speed, and joint comfort improvements by six months.
Flavor and quality graphic for Metagenics OmegaGenics® 3‑in‑1 Fish Oil 720 mg EPA‑DHA showing a bottle of the product surrounded by lemons and limes with text highlighting that cleaner oils have cleaner taste and natural fruit flavors improve palatability.
Quality‑standards graphic for Metagenics OmegaGenics® 3‑in‑1 Fish Oil 720 mg EPA‑DHA showing a person holding a capsule with text listing six indicators of high‑quality fish oil: concentrated EPA and DHA, high absorption, guaranteed purity, certified sustainable sourcing, freshness with no oxidation, and professional‑grade formulation.
Omega-3s & Fish Oil
Heart Health
Brain & Cognitive Health

New to Metagenics? Get 15% off your first order + free shipping! Auto-applied at checkout.

Select Container Size

Why OmegaGenics® 3-in-1 Fish Oil 720 mg EPA-DHA may be right for you

Omega-3s are essential nutrients your body simply can't make on its own, yet your heart, eyes, and joints depend on them daily. OmegaGenics® 3-in-1 Fish Oil 720 mg EPA-DHA is a high-quality, multi-benefit fish oil delivering 430 mg EPA and 290 mg DHA per softgel from 100% wild-caught fish and purified to the highest standards.

Why you'll love this OmegaGenics® fish oil:

  • Delivers 3-in-1 support: For heart, eye, and joint health.*
  • High potency: 720 mg of EPA and DHA per softgel
  • Everyday omega-3 support: Three key benefits supporting heart, eye, and joint health per daily dose*
  • Sustainably sourced: From wild-caught, small, cold-water fish for purity and sustainability
  • Better taste: Natural lemon-lime flavor for a clean finish and no fishy burps
  • Satisfaction Guaranteed: Love it within 60-days or your money back

The Science Inside

EPA and DHA are essential omega-3 fatty acids. Your body needs them daily, but most people can't get enough from diet alone. This formula delivers both, supporting 3 key benefits in daily use.*

  • EPA (eicosapentaenoic acid) — The heart and joint health omega-3. Supports cardiovascular health and helps keep your body's inflammatory response in balance. (430 mg per softgel)*
  • DHA (docosahexaenoic acid) — The eye omega-3. DHA supports eye health, focus, and clear vision. (290 mg per softgel)*
  • Natural lemon-lime flavor — A clean finish with no fishy aftertaste.

These omega-3s are sustainably sourced, Friend of the Sea certified, and rigorously purified to ensure quality you can trust:

  • Friend of the Sea Certified ensuring responsible sourcing and environmental protection
  • Rigorously tested for 200+ contaminants, including heavy metals, environmental toxins, and microplastics
  • Derived from wild-caught sardines, anchovies, and mackerel—small fish chosen for purity and sustainability

Third-Party Tested. Practitioner Trusted.

For over 40 years, Metagenics® has led innovation in health supplements, exceeding industry standards for transparency and accountability. We guarantee that what’s on the label is what’s in the bottle, and that commitment is why we’re trusted by more than 50,000 healthcare providers worldwide. This, and all our formulas are also:

  • Produced in GMP and NSF-certified facilities to meet the highest quality standards.
  • Science-backed - We perform +200K tests annually, from ingredient sourcing to finished product, for accuracy and consistency.
  • Third-party Tested - All our products are independently verified for purity, potency, & safety.
  • Metagenics® is the #1 Doctor-Recommended Professional Supplement Brand trusted by 50,000 healthcare practitioners.
  • Environmentally Responsible - As a registered B-Corp, sustainability matters; all our products are made ethically, responsibly, and with purpose.
  • Risk Free - Every purchase is backed by our 60-Day Money Back Guarantee.

What’s Inside (and What’s Not)

Contains fish (sardine, anchovy, mackerel) | Contains gelatin | Contains glycerin | Non-GMO | Gluten-free | Lactose-free | No artificial colors or flavors | No preservatives

†† Richter CK, Bowen KJ. Total long-chain n-3 fatty acid intake and food sources in the United States compared to recommended intakes: NHANES 2003-2008. Lipids. 2017;52(11):917-927.

(1) Chevalier, L. & Plourde, M. et al., 2021. Pharmacokinetics of supplemental omega-3 fatty acids: Acute increases in plasma EPA and DHA within 24 hours after ingestion. Journal of Nutrition. doi:10.1093/jn/nxaaa1444

(2) U.S. Department of Health and Human Services, National Institutes of Health, Office of Dietary Supplements. (2024). Omega-3 fatty acids: Fact sheet for health professionals. https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/

(3) Borja-Magno, A. et al. (2023) ‘Differential effects of high-dose omega-3 fatty acids on metabolism and inflammation in patients with obesity: Eicosapentaenoic and docosahexaenoic acid supplementation’, Frontiers in Nutrition, 10, p. Article 1156995. doi: 10.3389/fnut.2023.1156995

(4) Gubari, M. I. M., 2024. Effect of omega-3 fatty acid supplementation on markers of inflammation and endothelial function in patients with chronic heart disease: A systematic review and meta-analysis. Cellular and Molecular Biology, 70(6), pp.171–177. doi:10.14715/cmb/2024.70.6.26.

(5)Xie, L. et al. (2025) ‘Effects of omega-3 fatty acids on chronic pain: A systematic review and meta-analysis’, Frontiers in Medicine, 12, Article 1654661. doi:10.3389/fmed.2025.1654661.

(6)Stavrinou, P. S. et al. (2020) ‘The effects of a 6-month high dose omega-3 and omega-6 polyunsaturated fatty acids and antioxidant vitamins supplementation on cognitive function and functional capacity in older adults with mild cognitive impairment’, Nutrients, 12(2), p. 325. doi:10.3390/nu12020325.

IngredientsAmount Per Serving% Daily Value
Serving Size2 Softgels
Servings Per Container30
Calories25
Calories from Fat25
Total Fat2.5 g3%**
Cholesterol5 mg2%
Marine Lipid Concentrate2.5 g***
EPA (Eicosapentaenoic acid)860 mg***
DHA (Docosahexaenoic acid)580 mg***
Other Omega-3 Fatty Acids160 mg***
**Percent Daily Values are based on a 2,000 calorie diet.***Daily Value not established.

Other Ingredients: Marine lipid concentrate [fish (sardine, anchovy, and mackerel) oil], softgel shell (gelatin, glycerin, water), contains 2 percent or less of natural lemon flavor, natural lime flavor, mixed tocopherols (antioxidant), rosemary extract, and ascorbyl palmitate (antioxidant). Contains: Fish (sardine, anchovy, and mackerel).



SKU: EPAL7

Take two softgels once daily with food or as directed by your healthcare practitioner.

Dry Place

Frequently bought together

Frequently Asked Questions

OmegaGenics® Fish Oil EPA-DHA 720 mg is a concentrated fish oil with DHA and EPA, delivering 430 mg EPA and 290 mg DHA per softgel to support heart, eye, and joint health.* and includes a natural lemon-lime flavor. Try it today backed by our 60-day money-back guarantee.

Take two softgels once daily with food or as directed by your healthcare practitioner. Start supporting your omega-3 levels today.

DHA (docosahexaenoic acid) is an essential building block of brain tissue and supports cognitive health and focus.* EPA helps maintain a healthy inflammatory response. Together, they provide foundational support for a healthy brain.* Start today with our 60-day money-back guarantee.

Metagenics® fish oil goes through rigorous testing at every stage, from sourcing to shelf. OmegaGenics® Fish Oil EPA-DHA 720 mg is tested for 200+ contaminants, produced in GMP and NSF-certified facilities, Friend of the Sea certified for sustainability, and independently verified for purity, potency, and safety.

OmegaGenics® Fish Oil EPA-DHA 720 mg is generally well-tolerated, but we recommend consulting your healthcare practitioner before combining it with other supplements or medications.

We stand behind every product. If you don't love OmegaGenics® Fish Oil EPA-DHA 720 mg within 60 days, we'll refund your purchase—no questions asked. Learn more about our 60-Day Money-Back Guarantee.

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