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Magtein® Magnesium L-Threonate

Support memory, focus, and mental clarity. Clinically studied to improve modeled cognitive age by 7.5 years^

Brain
Magnesium

Select Container Size

Why you'll love Magtein® Magnesium L-Threonate

Feel sharper and more focused with Magtein® Magnesium L-Threonate. This clinically studied form of magnesium supports brain health by helping you think clearly, remember details, and stay mentally engaged throughout your day. Whether you're dealing with brain fog, struggling to concentrate, or just want your brain to perform at its best, Magtein is designed to support the cognitive health you rely on every day.

  • Supports memory so you can recall information more easily*
  • Helps you maintain focus and concentration*
  • Supports clear thinking and decision-making*
  • May help reduce occasional brain fog*
  • May support healthy connections between brain cells (synapses)*

The Science Inside

  • How It Works: Magtein® is a special form of magnesium designed to cross the blood-brain barrier more easily, allowing it to reach brain cells more effectively. Once there, it can support healthy brain signaling and cognitive function. Magnesium is also critical for mitochondrial function, the energy "engines" inside every cell, including brain and nerve cells. By helping cells produce energy more efficiently, it supports working memory, focus, and overall cognitive performance.*
  • Key Ingredient: Each serving (3 capsules) provides 2 g Magtein® (magnesium L-threonate), delivering 147 mg elemental magnesium (35% Daily Value). This form was developed specifically for bioavailability and brain health.*

What makes Magtein® Magnesium L-Threonate different?

  • Backed by Research: Features a form of magnesium shown in research to support cognitive performance and mental sharpness.*
  • Brain-Health Focused: Unlike magnesium glycinate, which supports muscle relaxation and sleep, Magtein® is specifically formulated to support your brain's health and cognitive function.*
  • Clinical Results: Clinical studies show significant improvements in thinking and memory.*

^In a randomized, double-blind, placebo-controlled trial, Magtein® supplementation was associated with a statistically significant improvement in modeled cognitive age, corresponding to an estimated 7.5-year difference versus placebo, in healthy individuals age 18-45.

Lopresti AL and Smith SJ (2026) The effects of magnesium L-threonate (Magtein®) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial. Front. Nutr. 12:1729164

What is cognitive aging?

Cognitive aging describes changes in cognitive performance over time, including memory, processing speed, and attention. An estimated cognitive age is a modeled performance score that compares cognitive function to population norms, reflecting performance outcomes rather than biological age.


Third-party tested. Practitioner trusted.

For over 40 years, Metagenics® has led innovation in health supplements, exceeding industry standards for transparency and accountability. We guarantee that what’s on the label is what’s in the bottle, and that commitment is why we’re trusted by more than 50,000 healthcare providers worldwide. This, and all our formulas are also:

  • Produced in GMP and NSF-certified facilities to meet the highest quality standards.
  • Science-backed: We perform +200K quality tests annually, from ingredient sourcing to finished product, for accuracy and consistency.
  • Third-party Tested: All our products are independently verified for purity, potency, & safety.
  • Metagenics® is the #1 Doctor-Recommended Professional Supplement Brand trusted by 50,000 healthcare practitioners.
  • Environmentally Responsible: As a registered B-Corp, sustainability matters; all our products are made ethically, responsibly, and with purpose.
  • Risk Free: Every purchase is backed by our 60-Day Money Back Guarantee.

Allergen Information:

Non-GMO | Gluten-Free | Lactose-Free | Sugar-Free | Free From Artificial Preservatives | Vegetarian

IngredientsAmount Per Serving% Daily Value
Serving Size2 Capsules†
Servings Per Container60
Per Serving of 2 Capsules
Magnesium (as magnesium L-threonate)98 mg23%
Magnesium L-Threonate††1.3 g*
Per Serving of 3 Capsules
Magnesium (as magnesium L-threonate)147 mg35%
Magnesium L-Threonate††2 g*

Other Ingredients: Capsule (hydroxypropylmethylcellulose), microcrystalline cellulose, stearic acid (vegetable), and silica.



SKU: MAGLT

Recommended Dosage: Three capsules daily provide 2 g Magtein® (magnesium L-threonate) delivering 147 mg elemental magnesium. Best Time to Take: Take one capsule in the morning and two capsules approximately two hours before bedtime, or as directed by your healthcare provider. Who It's For: Adults seeking support for cognitive function and mental clarity. Safe for daily use.* Safety: If you are pregnant, nursing, taking medication, or have a medical condition, consult your healthcare practitioner before use. Keep out of reach of children.

Dry Place

Magtein® Magnesium L-Threonate

If pregnant or nursing, or taking medication, consult your healthcare practitioner before use. Keep out of the reach of children.

Frequently bought together

  • Magnesium Citrate

    Supports healthy muscle function.*

    4.5
    Magnesium Citrate
  • Ceriva®

    Supports memory and cognitive function*

    5.0
    Ceriva®
  • MyoCalm®

    Supports muscle relaxation*

    5.0
    MyoCalm®
A woman meditating with the headline “Magnesium L-Threonate supports your brain by:” followed by “Promoting synaptic plasticity” and “Supporting cellular energy.”
“Key benefits of Magnesium L-Threonate,” displays a hand holding a capsule alongside icons listing benefits: Brain health & cognition, Stronger memory, Faster focus, Deeper sleep, and More clarity.
“How it works inside your brain,” explains that a special form of magnesium is designed to cross into the brain more easily, passes through the blood-brain barrier for better delivery to brain cells, supports healthy brain signaling and cognitive function, and is essential for mitochondrial energy production in brain and nerve cells.
“The difference you’ll feel,” features a glowing brain illustration with callouts including a healthy stress response, brain health & cognition, healthy nerve function, balanced mood, and restful sleep.
Brain
Magnesium

Select Container Size

Why you'll love Magtein® Magnesium L-Threonate

Feel sharper and more focused with Magtein® Magnesium L-Threonate. This clinically studied form of magnesium supports brain health by helping you think clearly, remember details, and stay mentally engaged throughout your day. Whether you're dealing with brain fog, struggling to concentrate, or just want your brain to perform at its best, Magtein is designed to support the cognitive health you rely on every day.

  • Supports memory so you can recall information more easily*
  • Helps you maintain focus and concentration*
  • Supports clear thinking and decision-making*
  • May help reduce occasional brain fog*
  • May support healthy connections between brain cells (synapses)*

The Science Inside

  • How It Works: Magtein® is a special form of magnesium designed to cross the blood-brain barrier more easily, allowing it to reach brain cells more effectively. Once there, it can support healthy brain signaling and cognitive function. Magnesium is also critical for mitochondrial function, the energy "engines" inside every cell, including brain and nerve cells. By helping cells produce energy more efficiently, it supports working memory, focus, and overall cognitive performance.*
  • Key Ingredient: Each serving (3 capsules) provides 2 g Magtein® (magnesium L-threonate), delivering 147 mg elemental magnesium (35% Daily Value). This form was developed specifically for bioavailability and brain health.*

What makes Magtein® Magnesium L-Threonate different?

  • Backed by Research: Features a form of magnesium shown in research to support cognitive performance and mental sharpness.*
  • Brain-Health Focused: Unlike magnesium glycinate, which supports muscle relaxation and sleep, Magtein® is specifically formulated to support your brain's health and cognitive function.*
  • Clinical Results: Clinical studies show significant improvements in thinking and memory.*

^In a randomized, double-blind, placebo-controlled trial, Magtein® supplementation was associated with a statistically significant improvement in modeled cognitive age, corresponding to an estimated 7.5-year difference versus placebo, in healthy individuals age 18-45.

Lopresti AL and Smith SJ (2026) The effects of magnesium L-threonate (Magtein®) on cognitive performance and sleep quality in adults: a randomised, double-blind, placebo-controlled trial. Front. Nutr. 12:1729164

What is cognitive aging?

Cognitive aging describes changes in cognitive performance over time, including memory, processing speed, and attention. An estimated cognitive age is a modeled performance score that compares cognitive function to population norms, reflecting performance outcomes rather than biological age.


Third-party tested. Practitioner trusted.

For over 40 years, Metagenics® has led innovation in health supplements, exceeding industry standards for transparency and accountability. We guarantee that what’s on the label is what’s in the bottle, and that commitment is why we’re trusted by more than 50,000 healthcare providers worldwide. This, and all our formulas are also:

  • Produced in GMP and NSF-certified facilities to meet the highest quality standards.
  • Science-backed: We perform +200K quality tests annually, from ingredient sourcing to finished product, for accuracy and consistency.
  • Third-party Tested: All our products are independently verified for purity, potency, & safety.
  • Metagenics® is the #1 Doctor-Recommended Professional Supplement Brand trusted by 50,000 healthcare practitioners.
  • Environmentally Responsible: As a registered B-Corp, sustainability matters; all our products are made ethically, responsibly, and with purpose.
  • Risk Free: Every purchase is backed by our 60-Day Money Back Guarantee.

Allergen Information:

Non-GMO | Gluten-Free | Lactose-Free | Sugar-Free | Free From Artificial Preservatives | Vegetarian

IngredientsAmount Per Serving% Daily Value
Serving Size2 Capsules†
Servings Per Container60
Per Serving of 2 Capsules
Magnesium (as magnesium L-threonate)98 mg23%
Magnesium L-Threonate††1.3 g*
Per Serving of 3 Capsules
Magnesium (as magnesium L-threonate)147 mg35%
Magnesium L-Threonate††2 g*

Other Ingredients: Capsule (hydroxypropylmethylcellulose), microcrystalline cellulose, stearic acid (vegetable), and silica.



SKU: MAGLT

Recommended Dosage: Three capsules daily provide 2 g Magtein® (magnesium L-threonate) delivering 147 mg elemental magnesium. Best Time to Take: Take one capsule in the morning and two capsules approximately two hours before bedtime, or as directed by your healthcare provider. Who It's For: Adults seeking support for cognitive function and mental clarity. Safe for daily use.* Safety: If you are pregnant, nursing, taking medication, or have a medical condition, consult your healthcare practitioner before use. Keep out of reach of children.

Dry Place

Magtein® Magnesium L-Threonate

If pregnant or nursing, or taking medication, consult your healthcare practitioner before use. Keep out of the reach of children.

Frequently bought together

  • Magnesium Citrate

    Supports healthy muscle function.*

    4.5
    Magnesium Citrate
  • Ceriva®

    Supports memory and cognitive function*

    5.0
    Ceriva®
  • MyoCalm®

    Supports muscle relaxation*

    5.0
    MyoCalm®

Frequently Asked Questions

Take one capsule in the morning and two capsules about two hours before bedtime, or as directed by your healthcare provider. This timing is backed by research showing better memory and focus. Using it daily and consistently is key to getting the mental clarity benefits. Try Magtein risk-free with our 60-day money-back guarantee.

Magnesium glycinate is excellent for supporting muscle relaxation, sleep, and general magnesium supplementation. Magtein® Magnesium L-threonate is specifically formulated for brain health and cognitive support. Studies on Magtein show improvements in thinking, recall, and mental clarity If your goal is brain health, Magtein is the form backed by brain-specific research. Learn about different forms of magnesium and their benefits: Magnesium 101: The 4 Most Common Questions Explained.

In one study, better working memory was seen at 6 weeks, with continued benefits through the 12-week study. You may need to use it daily for at least a few weeks to notice cognitive support benefits. For more complete brain health support, consider Wellness Essentials Brain Health Daily Packs, which combines Magtein® with other vitamins, minerals and phytonutrients.

Yes, Magtein® Magnesium L-threonate is designed to support brain health and mental clarity. Research shows it supports memory, attention and decision-making by helping maintain the connections between brain cells and the energy your brain needs to think clearly and stay focused. Explore more support options for stress, mood and sleep.

Yes, Magtein is safe for daily, long-term use when taken as directed. The formulation has been studied by researchers, and each batch is third-party tested for purity, potency and safety. As with any supplement, consult your healthcare practitioner before use if you are pregnant, nursing, taking medication, or have a medical condition. Learn more about our rigorous quality standards.

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